1 |
Executive Summary |
1.1 |
Main Findings |
1.2 |
Main Conclusions |
1.3 |
Global Bio-Detection Market 2011-2016 |
1.3.1 |
Global Systems, Service & Upgrade Markets 2011-2016 |
1.3.2 |
Markets by Countries & Regions 2011-2016 |
1.3.3 |
Markets by Outdoor, Indoor, Hand-Held and Mobile Lab 2011-2016 |
1.3.4 |
Systems Market by Technology Generation 2011-2016 |
1.3.5 |
Service & Upgrade Market by Generation 2011-2016 |
1.4 |
Business Opportunities |
1.4.1 |
Bio-Surveillance, Detection & Bio-forensics Business Challenges 2011-2016 |
1.5 |
Technology Outlook |
2 |
Introduction |
2.1 |
Scope |
2.2 |
Who is This Report For? |
2.3 |
Methodology |
2.4 |
Terms of Reference |
3 |
Bio-Terror |
4 |
Forty Countries: Bio-Security Status Review |
4.1 |
Background |
4.2 |
Forty Countries Bio-Technology & Bio-Defense Performance Score |
5 |
Bio-Detection Market Drivers |
6 |
Bio-Detection Market Inhibitors |
7 |
Bio-Detection Industry Competitive Analysis |
8 |
Industry SWOT Analysis |
8.1 |
Scope |
8.2 |
SWOT Analysis |
9 |
The Bio-Detection Process |
9.1 |
Sampling the Environment |
9.2 |
Bio-Detectors in a Multitude of Ambient Settings |
9.3 |
Bio-Detection Triggering |
9.4 |
Sample Collection |
9.5 |
Bio-Particle Detectors |
9.6 |
Bio-Agent Identification |
10 |
Bio-Detection Technological Challenges |
10.1 |
Challenge 1 Detection of Small Particle Concentration |
10.2 |
Challenge 2 Bio-Background Suppression |
10.3 |
Challenge 3 Expensive Reagents |
10.4 |
Challenge 4 Expensive Equipment Maintenance |
10.5 |
Challenge 5 Adapting Equipment to Changing Environments |
10.6 |
Challenge 6 Dealing With Emerging Threats |
11 |
Present and Pipeline Bio-Detection Technologies |
11.1 |
Bio-Detection Core Technologies Comparison |
11.2 |
Collector/Concentrator Core Technologies |
11.3 |
Cyclone Collectors |
11.4 |
Variable Particle-Size Impactor |
11.5 |
Virtual Impactors |
11.6 |
Impingers |
11.7 |
Reagent-less Trigger Core Technologies |
11.7.1 |
Flow Cytometry |
11.7.2 |
Particle Sizing |
11.7.3 |
Gas Chromatography |
11.7.4 |
Trigger Technologies Drivers |
11.7.5 |
Trigger Technologies Inhibitors |
11.8 |
DNA Based Diagnostic Core Technologies |
11.8.1 |
Overview of DNA-Based Detection |
11.8.2 |
Polymerase Chain Reaction (PCR) |
11.8.3 |
DNA / RNA Microarrays |
11.8.4 |
DNA Technology Drivers |
11.8.5 |
DNA Technology Inhibitors |
11.9 |
Antibody-Antigen Diagnostic Core Technologies |
11.9.1 |
Overview of Antibody-Antigen Reaction |
11.9.2 |
Hand-Held Immuno-Chromatographic Assays (HHA) |
11.9.3 |
Magnetic Microbead-Base Assays |
11.9.4 |
Microfluidic Devices “Lab on a Chip” |
11.9.5 |
Fluorescence Imaging |
11.9.6 |
Electrochemical-Luminescence (ECL) |
11.9.7 |
Antibody/Antigen Technology Drivers |
11.9.8 |
Antibody/Antigen Technology Inhibitors |
11.1 |
Signal Analysis Algorithms |
11.10.1 |
Clustering / Classifier Algorithms |
11.10.2 |
Image Analysis Algorithms |
11.10.3 |
Decision Algorithms |
11.10.4 |
Drivers |
11.10.5 |
Inhibitors |
11.11 |
Rapid Microbiological Technologies |
12 |
Bio- Detection Analysis by Application |
12.1.1 |
Application 1 Emergency Responder Hand-Held Detectors |
12.1.2 |
Application 2 Emergency Responder Mobile Labs |
12.1.3 |
Application 3 Indoor Standoff Detectors |
12.1.4 |
Application 4 Outdoor Standoff Detectors |
13 |
Global Bio- Detection Market 2011-2016 |
13.1 |
The Global Market Overview |
13.2 |
Market by Systems, Upgrade and Service Segments 2011-2016 |
13.3 |
Global Market by Countries & Regions 2011-2016 |
13.4 |
Global Systems Market by Technological Generation 2011-2016 |
13.5 |
Global Systems Market by Indoor, Outdoor, Hand-Held and Mobile Labs Segments 2011-2016 |
13.6 |
Global Service & Upgrade Market 2011-2016 |
13.6.1 |
Global Service and Upgrade Business by Technological Generation 2011-2016 |
13.6.2 |
Global Service & Upgrade Market by Indoor, Outdoor, Hand-Held and Mobile Labs Segments 2011-2016 |
14 |
US Bio-Detection Market 2011-2016 |
14.1 |
US Bio-Defense Background & Analysis |
14.2 |
The Obama Administration Bio Terror Mitigation Strategy |
14.3 |
Biosurveillance Network |
14.4 |
Bio-Defense Funding |
14.4.1 |
Overview |
14.4.2 |
DHHS Bio-Defense Missions and Funding |
14.4.3 |
DHS Bio-Defense Missions and Funding |
14.4.4 |
DOD Bio-Defense Missions and Funding |
14.4.5 |
DOA Bio-Defense Missions and Funding |
14.4.6 |
EPA Bio-Defense Missions and Funding |
14.5 |
Leading Bio-Security Projects |
14.5.1 |
Project BioWatch |
14.5.2 |
Project BioSense |
14.5.3 |
Project BioShield |
14.6 |
Market Drivers |
14.7 |
Market Inhibitors |
14.8 |
US Bio-Detection Systems Market 2011-2016 |
14.8.1 |
Sales by Generation Forecast |
14.8.2 |
US Bio-Detection Systems Market by Modality Forecast |
14.9 |
US Outdoor Standoff Bio-Detection Systems Market 2011-2016 |
14.9.1 |
Sales Outlook |
14.1 |
US Indoor Bio-Detection Systems Market 2011-2016 |
14.10.1 |
Indoor Market Outlook |
14.11 |
US Hand-Held Detection Systems Market 2011-2016 |
14.11.1 |
Hand-Held Detection Systems Market Outlook |
14.12 |
US Mobile Bio-Detection Labs Market 2011-2016 |
14.12.1 |
Market Outlook |
14.13 |
US Service Business 2011-2016 |
14.13.1 |
Service & Upgrade Business by Modality 2011-2016 |
14.13.2 |
Service Business by Generation 2011-2016 |
15 |
The UK, Germany, France, Italy and Spain HLS-HLD Bio-Detection Market |
15.1 |
The European Union |
15.1.1 |
The European Union Bio-Defense Background |
15.1.2 |
EU Program of Cooperation on Preparedness and Response to Biological and Chemical Agent Attacks (BICHAT) |
15.1.3 |
EU Bio-Defense Research Programs |
15.2 |
The UK |
15.2.1 |
Bio-Defense Strategy |
15.2.2 |
Main Bio-Defense Initiatives |
15.3 |
Germany |
15.3.1 |
Bio-Defense Strategy |
15.3.2 |
Main Bio-Defense Initiatives |
15.3.3 |
Bio- Detection R&D Projects |
15.4 |
France |
15.5 |
Italy |
15.6 |
Spain |
15.7 |
Market Drivers |
15.8 |
Market Inhibitors |
15.9 |
UK, Germany, France, Italy and Spain Bio-Detection Systems Market 2011-2016 |
15.9.1 |
Sales by Technology Generations Forecast |
15.9.2 |
Sales by Modality Forecast |
15.1 |
UK, Germany, France, Italy and Spain Outdoor Standoff Bio-Detection Systems Market Forecast 2011-2016 |
15.10.1 |
Systems Market Outlook |
15.11 |
UK, Germany, France, Italy and Spain Indoor Bio-Detection Systems Market 2011-2016 |
15.11.1 |
Systems Market Outlook |
15.12 |
UK, Germany, France, Italy and Spain Hand-Held Detection Systems Market 2011-2016 |
15.12.1 |
Systems Market Outlook |
15.13 |
UK, Germany, France, Italy and Spain Mobile Bio-Detection Labs Market 2011-2016 |
15.13.1 |
Market Outlook |
15.14 |
UK, Germany, France, Italy and Spain Service Business 2011-2016 |
15.14.1 |
Service & Upgrade Business by Modality 2011-2016 |
15.14.2 |
Service Business by Generation 2011-2016 |
16 |
China, Taiwan, Japan, India and Middle East HLS-HLD Bio-Detection Market |
16.1 |
Asian Countries Bio- Defense Background |
16.2 |
Japan |
16.3 |
China |
16.4 |
Taiwan |
16.5 |
India |
16.6 |
Singapore |
16.7 |
Middle East |
16.8 |
Market Drivers |
16.9 |
Market Inhibitors |
16.1 |
China, Taiwan, Japan, India and Middle East Bio-Detection Systems Market 2011-2016 |
16.10.1 |
Sales by Technology Generation 2011-2016 |
16.10.2 |
Market by Modality 2011-2016 |
16.11 |
China, Taiwan, Japan, India and Middle East Bio-Detection Outdoor Systems Market 2011-2016 |
16.11.1 |
Sales Outlook |
16.12 |
China, Taiwan, Japan, India and Middle East Bio-Detection Indoor Systems Market 2011-2016 |
16.12.1 |
Market Outlook |
16.13 |
China, Taiwan, Japan, India and Middle East Hand-Held Detection Systems Market 2011-2016 |
16.13.1 |
Market Outlook |
16.14 |
China, Taiwan, Japan, India and Middle East Bio-Detection Mobile Labs Market 2011-2016 |
16.14.1 |
Market Outlook |
16.15 |
China, Taiwan, Japan, India and Middle East Service Business 2011-2016 |
16.15.1 |
Service & Upgrade Business by Modality 2011-2016 |
16.15.2 |
Service Business by Generation 2011-2016 |
17 |
The Rest of the World HLS-HLD Bio-Detection Market |
17.1 |
ROW: Bio-Defense Background |
17.1.1 |
Russia and CIS |
17.1.2 |
Russian Government Bio-Security Initiatives |
17.1.3 |
International Science and Technology Center (ISTC) |
17.1.4 |
Canada |
17.1.5 |
Australia |
17.2 |
Market Drivers |
17.3 |
Market Inhibitors |
17.4 |
ROW Bio-Detection Systems Market 2011-2016 |
17.4.1 |
Sales Forecast by Generation |
17.4.2 |
Market by Modality Forecast |
17.5 |
ROW Outdoor Bio-Detection Systems Market 2011-2016 |
17.5.1 |
Sales Outlook |
17.6 |
ROW Indoor Bio-Detection Systems Market 2011-2016 |
17.6.1 |
Market Outlook |
17.7 |
ROW Hand-Held Detection Systems Market 2011-2016 |
17.7.1 |
ROW Market Outlook |
17.8 |
ROW Mobile Bio-Detection Labs Market 2011-2016 |
17.8.1 |
Market Outlook |
17.9 |
ROW Service Business 2011-2016 |
17.9.1 |
ROW Service & Upgrade Business by Modality |
17.9.2 |
Service Business by Generation 2011-2016 |
18 |
Bio-Detection Business Opportunities 2011-2016 |
18.1 |
Historical Perspective: A Market Waiting for Transition |
18.1.1 |
The Current and Future HLS Bio-Defense Strategy for Detection |
18.1.2 |
Factors Affecting Biological Detectors Deployment and Technologies 2011-2016 |
18.1.3 |
Biological Detection Technology Timeline |
18.2 |
Business Opportunities for Next Generation HLS Bio-Detection Systems |
18.2.1 |
Business Opportunity 1 Emerging Threats |
18.2.2 |
Business Opportunity 2 Human Sentinel Surveillance System |
18.2.3 |
Business Opportunity 3 Animal Sentinel Surveillance System |
18.2.4 |
Business Opportunity 4 Biological IC3 Biological Threat Assessment Intelligence Command, Control, and Communication Infrastructure |
18.2.5 |
Business Opportunity 5 Reducing False Alarms Less False Positives and False Negatives |
18.2.6 |
Business Opportunity 6 Reducing Cost Minimizing Use of Non-Reusable Reagents |
18.3 |
Outdoor Standoff Biological Detectors |
18.3.1 |
Business Opportunity 7 Bio-agent Autonomous Networked Detectors (BAND) |
18.3.2 |
Business Opportunity 8 Rapid Automated Biological Identification System (RABIS) |
18.3.3 |
Business Opportunity 9 First Responder Portable Hand-Held Detector |
18.3.4 |
Business Opportunity 10 First-Responder Mobile Biological Detection Station |
18.3.5 |
Business Opportunity 11 Regional Automatic Detector Outdoor Standoff Detectors |
18.3.6 |
Business Opportunity 12 Networked Automatic Detector Indoor Standoff Detectors |
18.3.7 |
Business Opportunity 13 External Dissemination of Bio-Agent Detection |
18.3.8 |
Business Opportunity 14 Internal Dissemination of Bio-Agent |
18.4 |
Other Bio-Detection Technologies Business Opportunities |
18.4.1 |
Business Opportunity 15 “Lab on a Chip” Miniature Detection Devices |
18.4.2 |
Business Opportunity 16 Reagent-less Specific Detection Assays |
18.4.3 |
Business Opportunity 17 Laser-Induced Breakdown Spectroscopy (LIBS) |
18.4.4 |
Business Opportunity 18 Raman Spectroscopy-based Reagent-less Detection |
18.5 |
Future Technologies and Systems |
19 |
Vendors |
19.1 |
20/20 GeneSystems Inc. |
19.2 |
Advnt Biotechnologies |
19.3 |
Agilent Technologies |
19.4 |
Alexeter Technologies |
19.5 |
ANP Technologies, Inc. |
19.6 |
BAS – Biological Alarm Systems Ltd. (Israel) |
19.7 |
BD Biosciences Immunocytometry Systems |
19.8 |
Bertin Technologies |
19.9 |
BioDefense Corporation |
19.1 |
BioDETECT AS |
19.11 |
BioSentinel Pharmaceuticals LLC |
19.12 |
3M Microbiology (Biotrace International, Ltd.) |
19.13 |
BioTraces, Inc. |
19.14 |
BioVeris Corporation |
19.15 |
Biral |
19.16 |
Cepheid |
19.17 |
Commonwealth Biotechnologies, Inc. |
19.18 |
Dycor Technologies Ltd. |
19.19 |
Environics Oy |
19.2 |
Evogen, Inc. |
19.21 |
General Dynamics Canada |
19.22 |
GenPrime, Inc. |
19.23 |
Groton Biosystems |
19.24 |
Haztech Systems, Inc. |
19.25 |
Idaho Technology, Inc. |
19.26 |
JMAR Technologies, Inc. |
19.27 |
New Horizons Diagnostics |
19.28 |
Proengin |
19.29 |
QTL Biodetection |
19.3 |
Research International |
19.31 |
Response Biomedical |
19.32 |
Roche Applied Science |
19.33 |
Smiths Detection |
19.34 |
Tetracore, Inc. |
20 |
Prices of Bio-Detection Equipment |
21 |
Appendix A: The Threat of Bio-Terror |
21.1 |
Biological Terror |
21.2 |
Bio-Weapons Historical Perspective |
21.3 |
Biological Terror Bacterial Agents |
21.3.1 |
Anthrax |
21.3.2 |
Cholera |
21.3.3 |
Plague |
21.3.4 |
Tularemia |
21.4 |
Biological Terror Viral Agents |
21.4.1 |
Smallpox |
21.4.2 |
Hemorrhagic Fever Viruses |
21.4.3 |
Venezuelan Equine Encephalitis |
21.5 |
Biological Terror Rickettsiae Agents |
21.5.1 |
Q Fever |
21.5.2 |
Typhus |
21.6 |
Biological Terror Toxins |
21.6.1 |
Botulinum Toxin |
21.6.2 |
Ricin |
21.6.3 |
Saxitoxin |
21.6.4 |
Staphylococcal Enterotoxin B (SEB) |
22 |
Appendix B: Legal Issues |
22.1 |
International / European Legislation / Agreements |
22.1.1 |
The Biological and Toxin Weapons Convention (BTWC) 1972 |
22.2 |
U.S. Bioterrorism Legislation |
22.3 |
The European Treaties & Legislation |
22.3.1 |
EU Program of Cooperation on Preparedness and Response to Biological and Chemical Agent Attacks (BICHAT) |