1 |
Executive Summary |
1.1 |
Main Findings |
1.2 |
Main Conclusions |
1.3 |
Global Bio-Detection Market 2012-2016 |
1.3.1 |
Global Bio-Detection Systems, Service & Upgrade Markets 2012-2016 |
1.3.2 |
Markets by Geography 2012-2016 |
1.3.3 |
Markets for Outdoor, Indoor, Hand-Held and Mobile Lab Modalities 2012-2016 |
1.3.4 |
Systems Market by Technology Generation 2012-2016 |
1.3.5 |
Service & Upgrade Market by Generation 2012-2016 |
1.4 |
Business Opportunities |
1.5 |
Technology Outlook |
2 |
Introduction |
2.1 |
Scope |
2.2 |
Who is This Report For? |
2.3 |
Methodology |
2.4 |
Terms of Reference |
3 |
Bio-Terror & Infectious Disease Outbreak Detection |
3.1 |
Bio Terror |
3.2 |
National Biosurveillance Components |
4 |
Forty Countries: Bio-Security Status Review |
4.1 |
Background |
4.2 |
Forty Countries Bio-Technology & Biosurveillance Performance |
5 |
Bio-Detection Market Drivers |
6 |
Bio-Detection Market Inhibitors |
7 |
Bio-Detection Industry Competitive Analysis |
8 |
Industry SWOT Analysis |
8.1 |
Scope |
8.2 |
SWOT Analysis |
9 |
Biosurveillance Technology and Policy Regimes |
9.1 |
System-Level Metrics and Risk Management |
10 |
Bio-detection RDT&E and Procurement Process |
10.1 |
New Technology Development and Testing & Evaluation Process |
10.2 |
Government Bio Detection Industry Relationship |
11 |
Biosurveillance ICT Market |
11.1 |
Background |
11.2 |
Principles for a National Biosurveillance ICT System |
11.3 |
National Biosurveillance Integration Systems (NBIS) |
12 |
The Bio-Detection Process |
12.1 |
Sampling the Environment |
12.2 |
Bio-Detectors in a Multitude of Ambient Settings |
12.3 |
Bio-Detection Triggering |
12.4 |
Sample Collection |
12.5 |
Bio-Particle Detectors |
12.6 |
Bio-Agent Identification |
13 |
Bio-Detection Technological Challenges |
13.1 |
Challenge 1 Detection of Small Particle Concentration |
13.2 |
Challenge 2 Bio-Background Suppression |
13.3 |
Challenge 3 Expensive Reagents |
13.4 |
Challenge 4 Expensive Equipment Maintenance |
13.5 |
Challenge 5 Adapting Equipment to Changing Environments |
13.6 |
Challenge 6 Dealing With Emerging Threats |
14 |
Present and Pipeline Bio-Detection Technologies |
14.1 |
Bio-Detection Core Technologies Comparison |
14.2 |
Collector/Concentrator Core Technologies |
14.3 |
Cyclone Collectors |
14.4 |
Variable Particle-Size Impactor |
14.5 |
Virtual Impactors |
14.6 |
Impingers |
14.7 |
Reagent-less Trigger Core Technologies |
14.7.1 |
Flow Cytometry |
14.7.2 |
Particle Sizing |
14.7.3 |
Gas Chromatography |
14.7.4 |
Trigger Technologies Drivers |
14.7.5 |
Trigger Technologies Inhibitors |
14.8 |
DNA Based Diagnostic Core Technologies |
14.8.1 |
Overview of DNA-Based Detection |
14.8.2 |
Polymerase Chain Reaction (PCR) |
14.9 |
Antibody-Antigen Diagnostic Core Technologies |
14.9.1 |
Overview of Antibody-Antigen Reaction |
14.9.2 |
Hand-Held Immuno-Chromatographic Assays (HHA) |
14.9.3 |
Magnetic Microbead-Base Assays |
14.9.4 |
Microfluidic Devices “Lab. on a Chip” |
14.9.5 |
Fluorescence Imaging |
14.9.6 |
Electrochemical-Luminescence (ECL) |
14.9.7 |
Antibody/Antigen Technology Drivers |
14.9.8 |
Antibody/Antigen Technology Inhibitors |
14.1 |
Signal Analysis Algorithms |
14.10.1 |
Clustering / Classifier Algorithms |
14.10.2 |
Image Analysis Algorithms |
14.10.3 |
Decision Algorithms |
14.10.4 |
Drivers |
14.10.5 |
Inhibitors |
14.11 |
Rapid Microbiological Technologies |
14.11.1 |
Types of Rapid Microbiological Methods |
14.12 |
Data Bases Development |
14.13 |
Remote Systems Capable of Triggering |
14.14 |
Optical Trigger Technology Spectroscopic Analysis |
14.15 |
Lightweight and Point Detection |
14.16 |
Artificial Intelligence Optimization of Spectrometers |
14.17 |
CBRN Countermeasures to Terrorism |
14.18 |
Flame and Incendiary Technology |
15 |
Bio-Terror & Infectious Disease Outbreak Mitigation R&D |
16 |
Bio- Detection Analysis by Application |
16.1 |
Application 1 Emergency Responder Hand-Held Detectors |
16.2 |
Application 2 Emergency Responder Mobile Labs |
16.3 |
Application 3 Indoor Standoff Detectors |
16.4 |
Application 4 Outdoor Standoff Detectors |
16.4.1 |
Overview |
16.4.2 |
Project BioWatch Dry Filter Unit |
17 |
Global Bio-Detection Market 2012-2016 |
17.1 |
The Global Market Overview |
17.2 |
Price List of 45 Bio-Detection Systems and Accessories |
17.3 |
Market by Systems, Upgrade and Service Segments 2012-2016 |
17.4 |
Global Market by Geography 2012-2016 |
17.5 |
Global Systems Market by Technological Generation 2012-2016 |
17.6 |
Global Systems Market by Indoor, Outdoor, Hand-Held and Mobile Labs Segments 2012-2016 |
17.7 |
Global Service & Upgrade Market 2012-2016 |
17.7.1 |
Global Service and Upgrade Business by Technological Generation 2012-2016 |
17.7.2 |
Global Service & Upgrade Market by Indoor, Outdoor, Hand-Held and Mobile Labs Segments 2012-2016 |
18 |
US Bio-Detection Market 2012-2016 |
18.1 |
US Bio-Surveillance Background & Analysis |
18.2 |
The Obama Administration Bio Terror Mitigation Strategy |
18.3 |
Biosurveillance Network |
18.4 |
Bio-Defense Funding |
18.4.1 |
Overview |
18.4.2 |
DHHS Bio-Defense Missions and Funding |
18.4.3 |
DHS Bio-Defense Missions and Funding |
18.4.4 |
DOD Bio-Defense Missions and Funding |
18.4.5 |
DOA Bio-Defense Missions and Funding |
18.4.6 |
EPA Bio-Defense Missions and Funding |
18.4.7 |
DOS Bio-Defense Missions and Funding |
18.4.8 |
NSF Bio-Defense Missions and Funding |
18.5 |
Leading Bio-Security Programs |
18.5.1 |
Project BioWatch |
18.5.2 |
Project BioSense |
18.5.3 |
Project BioShield |
18.6 |
Market Drivers |
18.7 |
Market Inhibitors |
18.8 |
US Bio-Detection Systems Market 2012-2016 |
18.8.1 |
Sales by Generation Forecast |
18.8.2 |
US Bio-Detection Systems Sale Market by Modality Forecast |
18.9 |
US Outdoor Standoff Bio-Detection Systems Sale Market 2012-2016 |
18.9.1 |
Assumptions |
18.9.2 |
Sales Outlook |
18.1 |
US Indoor Bio-Detection Systems Sale Market 2012-2016 |
18.10.1 |
Assumptions |
18.10.2 |
Sales Outlook |
18.11 |
US Hand-Held Detection Systems Sale Market 2012-2016 |
18.12 |
US Mobile Bio-Detection Labs Market 2012-2016 |
18.13 |
US Bio-Detection Service Business 2012-2016 |
18.13.1 |
Service & Upgrade Business by Modality 2012-2016 |
18.13.2 |
Service Business by Generation 2012-2016 |
19 |
The UK, Germany, France, Italy and Spain Bio-Detection Market 2012-2016 |
19.1 |
The EU: Biosurveillance Strategy & Market Background |
19.1.1 |
The European Union Bio-Defense Background |
19.1.2 |
EU Program of Cooperation on Preparedness and Response to Biological and Chemical Agent Attacks (BICHAT) |
19.1.3 |
EU Bio-Defense Research Programs |
19.2 |
The UK: National Biosurveillance Strategy & Market Background |
19.2.1 |
The UK Bio-Defense Strategy |
19.2.2 |
Main UK Bio-Defense Initiatives |
19.3 |
Germany: National Biosurveillance Strategy & Market Background |
19.3.1 |
The German Bio-Defense Strategy |
19.3.2 |
Germany Main Bio-Defense Initiatives |
19.3.3 |
Germany Bio- Detection R&D Projects |
19.4 |
France: National Biosurveillance Strategy & Market Background |
19.5 |
Italy: National Biosurveillance Strategy & Market Background |
19.6 |
Spain: National Biosurveillance Strategy & Market Background |
19.7 |
Market Drivers |
19.8 |
Market Inhibitors |
19.9 |
UK, Germany, France, Italy and Spain Bio-Detection Systems Market 2012-2016 |
19.9.1 |
Sales by Technology Generations Forecast |
19.9.2 |
Sales by Modality Forecast |
19.1 |
UK, Germany, France, Italy and Spain Outdoor Standoff Bio-Detection Systems Market 2012-2016 |
19.10.1 |
Assumptions |
19.10.2 |
Sales Outlook |
19.11 |
UK, Germany, France, Italy and Spain Indoor Bio-Detection Systems Market 2012-2016 |
19.11.1 |
Assumptions |
19.11.2 |
Sales Outlook |
19.12 |
UK, Germany, France, Italy and Spain Hand-Held Detection Systems Market 2012-2016 |
19.12.1 |
Overview |
19.12.2 |
Sales Outlook |
19.13 |
UK, Germany, France, Italy and Spain Mobile Bio-Detection Labs Market 2012-2016 |
19.14 |
UK, Germany, France, Italy and Spain Service Business 2012-2016 |
19.14.1 |
Bio-Detection Service & Upgrade Business by Modality 2012-2016 |
19.14.2 |
Bio-Detection Service & Upgrade Business by Generation 2012-2016 |
20 |
China, Taiwan, Japan, India and Middle East: Bio- Detection Market 2012-2016 |
20.1 |
Asian Countries Bio-Defense Background |
20.2 |
Japan: National Biosurveillance Strategy & Market Background |
20.3 |
China: National Biosurveillance Strategy & Market Background |
20.4 |
Taiwan: National Biosurveillance Strategy & Market Background |
20.5 |
India: National Biosurveillance Strategy & Market Background |
20.6 |
Singapore: National Biosurveillance Strategy & Market Background |
20.7 |
Middle East: Biosurveillance Strategies & Market Background |
20.8 |
Market Drivers |
20.9 |
Market Inhibitors |
20.1 |
China, Taiwan, Japan, India and Middle East Bio-Detection Systems Market 2012-2016 |
20.10.1 |
Sales by Technology Generation 2012-2016 |
20.10.2 |
Sales by Modality 2012-2016 |
20.11 |
China, Taiwan, Japan, India and Middle East Bio-Detection Outdoor Systems Market 2012-2016 |
20.11.1 |
Sales Outlook |
20.12 |
China, Taiwan, Japan, India and Middle East Bio-Detection Indoor Systems Market 2012-2016 |
20.12.1 |
Assumptions |
20.12.2 |
Sales Outlook |
20.13 |
China, Taiwan, Japan, India and Middle East Hand-Held Detection Systems Market 2012-2016 |
20.13.1 |
Overview |
20.13.2 |
Sales Outlook |
20.14 |
China, Taiwan, Japan, India and Middle East Bio-Detection Mobile Labs Market 2012-2016 |
20.14.1 |
Sales Outlook |
20.15 |
China, Taiwan, Japan, India and Middle East Bio-Detection Service & Upgrade Business 2012-2016 |
20.15.1 |
Service & Upgrade Business by Modality 2012-2016 |
20.15.2 |
Service Business by Generation 2012-2016 |
21 |
The Rest of the World Bio-Detection Market 2012-2016 |
21.1 |
ROW: Bio-Defense Background |
21.1.1 |
Russia: National Biosurveillance Strategy & Market Background |
21.1.2 |
Russian Government Bio-Security Initiatives |
21.1.3 |
International Science and Technology Center (ISTC) |
21.1.4 |
Canada: National Biosurveillance Strategy & Market Background |
21.1.5 |
Australia |
21.2 |
Market Drivers |
21.3 |
Market Inhibitors |
21.4 |
ROW Bio-Detection Systems Market 2012-2016 |
21.4.1 |
Sales Forecast by Generation |
21.4.2 |
Sales by Modality |
21.5 |
ROW Outdoor Bio-Detection Systems Market 2012-2016 |
21.5.1 |
Sales Outlook |
21.6 |
ROW Indoor Bio-Detection Systems Market 2012-2016 |
21.6.1 |
Assumptions |
21.6.2 |
Sales Outlook |
21.7 |
ROW Hand-Held Detection Systems Market 2012-2016 |
21.7.1 |
Sales Outlook |
21.8 |
ROW Mobile Bio-Detection Labs Market 2012-2016 |
21.8.1 |
Sales Outlook |
21.9 |
ROW Bio-Detection Service & Upgrade Business 2012-2016 |
21.9.1 |
Bio-Detection Service & Upgrade Business by Modality |
21.9.2 |
Bio-Detection Service & Upgrade Business by Generation 2012-2016 |
22 |
Bio-Detection Business Opportunities 2012-2016 |
22.1 |
Historical Perspective: A Market Waiting for Transition |
22.2 |
Business Opportunities for Next Generation Bio-Terror & Outbreak Detection Systems |
22.2.1 |
Business Opportunity 1 Emerging Threats |
22.2.2 |
Business Opportunity 2 Human Sentinel Surveillance System |
22.2.3 |
Business Opportunity 3 Animal Sentinel Surveillance System |
22.2.4 |
Business Opportunity 4 Biological IC3 Infrastructure |
22.2.5 |
Business Opportunity 5 Reducing False Alarms |
22.2.6 |
Business Opportunity 6 Reducing Cost |
22.3 |
Outdoor Standoff Biological Detectors Business Opportunities |
22.3.1 |
Business Opportunity 7 Bio-agent Autonomous Networked Detectors (BAND) |
22.3.2 |
Business Opportunity 8 Rapid Automated Biological Identification System (RABIS) |
22.3.3 |
Business Opportunity 9 First Responder Portable Hand-Held Detector |
22.3.4 |
Business Opportunity 10 First-Responder Mobile Biological Detection Station |
22.3.5 |
Business Opportunity 11 Regional Automatic Detector Outdoor Standoff Detectors |
22.3.6 |
Business Opportunity 12 Networked Automatic Detector Indoor Standoff Detectors |
22.3.7 |
Business Opportunity 13 External Dissemination of Bio-Agent Detection |
22.3.8 |
Business Opportunity 14 Internal Dissemination of Bio-Agent |
22.4 |
Other Bio-Detection Technologies Business Opportunities |
22.4.1 |
Business Opportunity 15 “Lab on a Chip” Miniature Detection Devices |
22.4.2 |
Business Opportunity 16 Reagent-less Specific Detection Assays |
22.4.3 |
Business Opportunity 17 Laser-Induced Breakdown Spectroscopy (LIBS) |
22.5 |
Future Technologies and Systems |
23 |
Biosurveillance, Detection & Bio-forensics Business Challenges 2012-2016 |
23.1 |
Bio-informatics |
23.2 |
Advanced Sampling |
23.3 |
Sample Preparation |
23.4 |
Assays, RDT&E |
23.5 |
Bio-detection Instruments |
23.6 |
Data Analysis, Storage, Interoperability and Preservation |
23.7 |
Response and Recovery RDT&E |
23.8 |
Bio-Forensics (Microbial Forensics) |
23.9 |
Advanced Sample Preparation |
23.1 |
Physical and Chemical Analysis |
23.11 |
Molecular Signature Analysis |
23.12 |
Bacterial Population Genetics |
23.13 |
Viral Genetic Stability |
23.14 |
Host Pathogen Interactions |
23.15 |
Bio-informatics |
23.16 |
Bio-therapeutics |
24 |
Vendors |
24.1 |
20/20 GeneSystems Inc. |
24.2 |
Advnt Biotechnologies |
24.3 |
Agilent Technologies |
24.4 |
Alexeter Technologies |
24.5 |
ANP Technologies, Inc. |
24.6 |
BAS – Biological Alarm Systems Ltd. (Israel) |
24.7 |
BD Biosciences Immunocytometry Systems |
24.8 |
Bertin Technologies |
24.9 |
Biodefense Corporation |
24.1 |
BioDETECT AS |
24.11 |
BioSentinel Pharmaceuticals LLC |
24.12 |
3M Microbiology (Biotrace International, Ltd.) |
24.13 |
BioTraces, Inc. |
24.14 |
BioVeris Corporation |
24.15 |
Biral |
24.16 |
Cepheid |
24.17 |
Commonwealth Biotechnologies, Inc. |
24.18 |
Dycor Technologies Ltd. |
24.19 |
Environics Oy |
24.2 |
Evogen, Inc. |
24.21 |
General Dynamics Canada |
24.22 |
GenPrime, Inc. |
24.23 |
Groton Biosystems |
24.24 |
Haztech Systems, Inc. |
24.25 |
Idaho Technology, Inc. |
24.26 |
JMAR Technologies, Inc. |
24.27 |
New Horizons Diagnostics |
24.28 |
Proengin |
24.29 |
QTL Biodetection |
24.3 |
Research International |
24.31 |
Response Biomedical |
24.32 |
Roche Applied Science |
24.33 |
Smiths Detection |
24.34 |
Tetracore, Inc. |
25 |
Appendix A: The Threat of Bio-Terror and Infectious Disease Outbreak |
25.1 |
Biological Terror |
25.2 |
Bio-Weapons Historical Perspective |
25.3 |
Biological Terror Bacterial Agents |
25.4 |
Biological Terror Viral Agents |
25.5 |
Biological Terror Rickettsiae Agents |
25.6 |
Biological Terror Toxins |
26 |
Appendix B: Legal Issues |
26.1 |
Biosurveillance International Legislation |
26.2 |
U.S. Bioterrorism And Biosurveillance Legislation |
26.3 |
The European Treaties & Legislation |
27 |
Appendix C: Biosurveillance Acronym Glossary |
28 |
Appendix D: Key Bio-Terror and Infectious Disease Outbreak References |